Frequently asked questions

Explore frequently asked questions about Colgate® Sensitive Pro-Relief™ toothpaste, including ingredients, accessories and usage guidelines.

How do you open the cap?

The Colgate® Sensitive Pro-Relief™ tube has a unique tamper evidence safety seal. To open this safety seal, use the top of the cap as shown in the enclosed leaflet. Make the top of the cap fit securely with the crown shape on the tube and then twist the cap to break the seal open.

How do you open the cap?

How does the Colgate® Sensitive Pro-Relief™ with Pro-Argin®Technology provide instant relief?

Colgate® Sensitive Pro-Relief™ products instantly relieve sensitivity by physically plugging open dentine tubules, which helps block pain sensations from reaching the tooth nerves. Providing instant relief when massaged directly onto the tooth with your fingertip for one minute, and lasting relief when used regularly.


What is the unique combination of ingredients in the Colgate®Sensitive Pro-Relief™ toothpaste?

The unique combination of ingredients in Colgate® Sensitive Pro-Relief™ is arginine and the insoluble calcium compound, calcium carbonate.


What is Pro-Argin®?

"Pro-Argin®" is Colgate’s trademark name for the technology consisting of arginine and an insoluble calcium compound. In Colgate® Sensitive Pro-Relief™ products, the insoluble calcium compound is calcium carbonate.


What does Pro-Argin® do?

Ordinary sensitive toothpastes with potassium salts work by desensitising tooth pain over time. However, pain triggers can still reach the nerves via the open tubules.

Colgate® Sensitive Pro-Relief™ works differently. Pro-Argin® plugs and seals these dentine tubules, which helps block pain triggers to deliver instant* and ^lasting relief.


What is the source of your arginine? Natural or synthetic?

The arginine used in Colgate® Sensitive Pro-Relief™ products is naturally derived from plant/vegetable sources.


How much arginine is in the Colgate® Sensitive Pro-Relief™ products/toothpaste?

Arginine is present at 8% in the toothpaste formula.


Are there any safety issues related to the direct application of toothpaste with fluoride and/or arginine?

When used as directed, there are no safety issues for the direct application of Colgate®Sensitive Pro-Relief™ toothpaste. Do not use in children 6 years of age or less. For children 7 to 12 years of age, use only on the advice of a dentist or doctor.


Does this toothpaste protect my teeth from cavities?

Yes, Colgate® Sensitive Pro-Relief™ contains fluoride that effectively protects teeth from cavities the same as your standard fluoride toothpaste.


If a mouthwash is used after brushing with Colgate® Sensitive Pro-Relief™ will this counteract the benefit?

We are not aware of any common mouthwash ingredients that would counteract the efficacy of the product.


Can I use Colgate® Sensitive Pro-Relief™ toothpaste every day?

Yes. It is recommended that you use Colgate® Sensitive Pro-Relief™ toothpaste twice a day or as directed by a dentist for lasting relief.


Can I alternate with another toothpaste? 

Yes, you can tailor your oral care regime to suit your oral health needs. It's best though to consult with your dental professional to be sure you're using the best combination.


Do I ever need to take a break from using it?

Colgate® Sensitive Pro-Relief™ toothpaste contains fluoride for every day cavity protection and is ideal for everyday ongoing use.


What if my sensitivity returns?

If your tooth sensitivity returns, you'll need to use the sensitivity paste more often. The recommendation is twice daily brushing. Remember to raise this with your dental professional when you visit them.


Does Colgate® Sensitive Pro-Relief™ contain fluoride?

Yes, Colgate® Sensitive Pro-Relief™ contains 1450ppm fluoride to provide effective cavity protection. 


What makes Colgate® Sensitive Pro-Relief™ different from most other sensitive toothpastes?

Most other sensitivity toothpastes contain potassium which desensitises the pain of sensitivity. Potassium toothpastes take at least 2 weeks of use before significant sensitivity pain relief is delivered. Colgate® Sensitive Pro-Relief™ effectively plugs and seals open dentine tubules, the cause of sensitivity pain. This prevents pain producing stimuli, such as heat and cold, from causing pain sensations. Colgate® Sensitive Pro-Relief™ provides instant relief when directly applied with fingertip to a sensitive tooth and massaged for one minute. It provides lasting relief when you brush your teeth twice daily. 


Does it have to be used with any special toothbrush?

No, but you might want to use a brush with soft bristles that is specially designed for sensitive teeth, like the Colgate® 360° Sensitive Pro-Relief™ toothbrush. 


Is this product safe for infants and children?

Children typically do not experience hypersensitivity. Infants typically use toothpastes with a specially formulated lower level of fluoride. Do not use in children 6 years of age or less.


What is the difference between Colgate® Sensitive and Colgate®Sensitive Pro-Relief™ toothpastes? How do I choose the best option for me?

Colgate® Sensitive Pro-Relief™ toothpaste, when applied directly offers instant sensitivity relief and with continuous use, long lasting sensitivity relief. While Colgate® Sensitive Pro-Relief™ is a new way of treating sensitive teeth, we are also committed to providing consumers with a range of different offerings in the sensitive segment, and continue to offer our other Colgate® Sensitive toothpaste variants. 


Whitening treatments sometimes make my teeth sensitive. Does this product work in this case?

At this stage, we do not have dedicated clinical studies measuring sensitivity relief in conjunction with whitening treatments. However, we have no reason to believe that Colgate® Sensitive Pro-Relief™ toothpaste would not provide relief in these circumstances when used as directed.


Where can I find Colgate® Sensitive Pro-Relief™ mouthwash and the Colgate® Sensitive Pro-Relief™ Sensitivity Relief Pen + Sensitive Toothbrush?

These products are no longer sold in Australia and New Zealand:

    Colgate® Sensitive Pro-Relief™ mouthwash

    Colgate® Sensitive Pro-Relief™ Sensitivity Relief Pen + Sensitive Toothbrush

Please note the Colgate® 360° Sensitive Pro-Relief™ toothbrush is available.


*For instant relief, apply directly to each sensitive tooth with fingertip for one minute
^For lasting relief, brush twice daily

Further questions?

If you have any further questions which have not been answered above please contact our call centre, (Free Call) 1800 802 307 (Australia) or 0800 441 740 (New Zealand).

How does Pro-Argin® Technology work?

Pro-Argin® Technology is designed to provide instant and lasting relief for dentine hypersensitivity.

Schematic illustration of Pro-Argin® mode of action.
For instant relief, apply directly to each sensitive tooth with fingertip and gently massage for 1 minute. For lasting relief, apply to a gentle toothbrush making sure to brush all sensitive areas, brush twice daily.


Pro-Argin® Technology


This page/article is intended to promote understanding of and knowledge about general oral health topics. It is not intended to be a substitute for professional advice, diagnosis or treatment. Always seek the advice of your dentist or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment. Always read the label. Follow the directions for use. If symptoms persist, talk to your health professional.

For instant relief, apply directly to sensitive tooth with fingertip for one minute. For lasting relief, brush twice daily.
†Repairs with twice daily brushing to block the channels leading to sensitive teeth.